Norepinephrine-elicited accumulation of cyclic AMP in slices of rat cerebral cortex polarized with a weak anodal current.
نویسندگان
چکیده
Cyclic AMP accumulation in response to norepinephrine was examined in slices of rat cerebral cortex the day after a unilateral application of anodal current of 0.3, 3.0 or 30 microA to the surface of the sensorimotor cortex. When 3.0 microA was applied, the norepinephrine-elicited accumulation of cyclic AMP was greater in the cortical area including the application point than in either the contralateral cortical area or non-polarized control cortical slices. The changes in cyclic AMP accumulation are discussed in relation to the role of the direct current in producing functional changes in the cortex.
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عنوان ژورنال:
- Acta medica Okayama
دوره 41 6 شماره
صفحات -
تاریخ انتشار 1987